4902 Tobramycin

Components
NAME METHOD REFERENCE RANGE UNITS
Tobramycin EMIT  REFERENCE RANGE for Tobramycin:
Peak Therapeutic Level: 5.0 - 10.0 ug/mL
Trough Level: 1.0 - 2.0 ug/mL 
ug/mL 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Serum 1 (0.2) mL   Refrigerated - 7 Day(s), Frozen - 2 Month(s) Red top serum separator tubes are not acceptable. 


Clinical utility
Tobramycin is one of the aminoglycoside class of bactericidal drugs, also including streptomycin, neomycin, netilmycin, sisomycin, gentamycin, kanamycine, and amikacin. Due to toxic effects associated with aminoglycosides manifest as delayed-onset vestibular and cochlear sensory cell destruction and acute renal tubular necrosis, the goal of monitoring is to maintain therapeutic plasma concentration at minimum risk to patients.


Collection Instruction
For peak concentration, collect specimen at the end of the
infusion or 30-90 minutes after IM administration. For
trough concentration, collect specimen within 30 minutes
before adminstration of next dose. Serum separator tubes
are not acceptable.


Reported: Same day

CPT Code: 80200