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NAME | METHOD | REFERENCE RANGE | UNITS |
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Cocaine | LC-MS-MS | < 100 | ng/mL |
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Benzoylecgonine | LC-MS-MS | < 50 | ng/mL |
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Ecgonine Methylester | LC-MS-MS | < 50 | ng/mL |
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Cocaethylene | LC-MS-MS | < 50 | ng/mL |
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TYPE | VOLUME | TEMPERATURE | INSTRUCTIONS |
PRIMARY | ||||
1 | Serum | 5 (2.5) mL | Refrigerated - 72 Hour(s), Frozen - 7 Day(s) |
Cocaine is metabolized mainly to benzoylecgonine and ecgonine methylester. Cocaethylene is an indication of concurrent cocaine and alcohol consumption. Hydroxybenzoylecgonine is a metabolite mainly present in meconium. Serum half-life of cocaine is 1-5 hours. Benzoylecgonine appears in circulation 15-30 minutes after cocaine administration. Elimination half-life of benzoylecgonine is 5-6 hours. Benzoylecgonine will be detectable in urine after 2-3 hours and urine remains positive for 2-3 days (longer for chronic abusers) after cocaine use. |
Do not use serum separator tubes.
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