4170 Cocaine and Metabolites Confirmation Serum

Components
NAME METHOD REFERENCE RANGE UNITS
Cocaine LC-MS-MS  < 100  ng/mL 
Benzoylecgonine LC-MS-MS  < 50  ng/mL 
Ecgonine Methylester LC-MS-MS  < 50  ng/mL 
Cocaethylene LC-MS-MS  < 50  ng/mL 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Serum 5 (2.5) mL   Refrigerated - 72 Hour(s), Frozen - 7 Day(s)  


Clinical utility
Cocaine is metabolized mainly to benzoylecgonine and ecgonine methylester. Cocaethylene is an indication of concurrent cocaine and alcohol consumption. Hydroxybenzoylecgonine is a metabolite mainly present in meconium. Serum half-life of cocaine is 1-5 hours. Benzoylecgonine appears in circulation 15-30 minutes after cocaine administration. Elimination half-life of benzoylecgonine is 5-6 hours. Benzoylecgonine will be detectable in urine after 2-3 hours and urine remains positive for 2-3 days (longer for chronic abusers) after cocaine use.


Collection Instruction
Do not use serum separator tubes.


Reported: Same day

CPT Code: 82520

Notes: This test is for clinical purposes only. Reference ranges indicate reporting limits. This test is not approved for the testing of patient samples from New York State.