4937 Oxcarbazepine (Trileptal®)

Components
NAME METHOD REFERENCE RANGE UNITS
Oxcarbazepine Metabolite HPLC  10 - 35  ug/mL 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Serum 2 (1) mL   Ambient - 5 Day(s), Refrigerated - 14 Day(s), Frozen - 2 Month(s) See COLLECTION INSTRUCTIONS. 
ALTERNATE
  Plasma EDTA 2 (1) mL   Ambient - 5 Day(s), Refrigerated - 14 Day(s), Frozen - 2 Month(s)  


Clinical utility
Therapeutic drug monitoring of antiepileptic therapy. Oxcarbazepine is measured as its 10-hydroxy metabolite. Peak plasma concentrations of 10-hydroxyoxcarbazepine occur 4-6 hours after a single dose of oxcarbazepine. Elimination half-life of oxcarbazepine is 1-2.5 hours, whereas the elimination half-life of 10-hydroxyoxcarbazepine averages 9.3 +/- 1.8 hours after administration of a single dose.


Collection Instruction
SST tubes are not acceptable.


Reported: Same day

CPT Code: 80299