1398 Glucose-6 Phosphate Dehydrogenase (G-6-PDH)

Components
NAME METHOD REFERENCE RANGE UNITS
Glucose-6-Phosphate Dehydrogenase KS  7 - 20  U/g Hb 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Whole Blood EDTA 7 (2) mL   Refrigerated - 4 Day(s)  
ALTERNATE
  Whole Blood EDTA Microtai 7 (2) mL   Refrigerated - 4 Day(s)  


Clinical utility
A deficiency of G-6-PDH (glucose-6-phosphate dehydrogenase) causes hemolytic anemia. This sex-linked genetic defect involves approximately 2-3% of the world population. It is characterized by deficient concentrations of G-6-PD in erythrocytes but normal levels in leukocytes and platelets. These individuals develop hemolysis on exposure to a number of drugs and other stresses, including various infections. A severe form of G-6-PD deficiency, characterized by deficiency in leukocytes and erythrocytes is seen in Caucasians, American Indians, and Asians. Deficiency is related to the inability to maintain adequate levels of reduced glutathione in erythrocytes on exposure to offending agents.


Reported: Same day

CPT Code: 82955

Notes: Note CPT Code: 82955.