3102 Adrenocorticotropic Hormone (ACTH)

Components
NAME METHOD REFERENCE RANGE UNITS
Adrenocorticotropic Hormone ICMA  6 - 46  pg/mL 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Plasma EDTA 1 (0.5) mL   Frozen - 31 Day(s) Split into 2 plastic vials and freeze within 1 hour. 


Clinical utility
Aid in diagnosing disorders of the hypothalamic-pituitary system including ACTH-secreting tumors. In adrenal insufficiency, a concentration of ACTH greater than 100 pg/mL is diagnostic of primary adrenal insufficiency; whereas, patients with pituitary causes of adrenal insufficiency have ACTH concentrations in the normal range. In hypercortisolism (plasma cortisol greater than 15 ug/dL), an ACTH concentration of less than 5 pg/mL indicates that the cortisol secretion is ACTH-independent, usually an adrenal tumor or hyperplasia. An ACTH concentration of greater than 15 pg/mL indicates ACTH-dependent hypercortisolism, usually of pituitary origin, or occasionally ectopic ACTH secretion.


Collection Instruction
Plasma samples should be placed in plastic tubes and frozen
immediately. Avoid freeze/thaw cycles.


Reported: Same day

CPT Code: 82024