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NAME | METHOD | REFERENCE RANGE | UNITS |
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Adrenocorticotropic Hormone | ICMA | 6 - 46 | pg/mL |
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TYPE | VOLUME | TEMPERATURE | INSTRUCTIONS |
PRIMARY | ||||
1 | Plasma EDTA | 1 (0.5) mL | Frozen - 31 Day(s) | Split into 2 plastic vials and freeze within 1 hour. |
Aid in diagnosing disorders of the hypothalamic-pituitary system including ACTH-secreting tumors. In adrenal insufficiency, a concentration of ACTH greater than 100 pg/mL is diagnostic of primary adrenal insufficiency; whereas, patients with pituitary causes of adrenal insufficiency have ACTH concentrations in the normal range. In hypercortisolism (plasma cortisol greater than 15 ug/dL), an ACTH concentration of less than 5 pg/mL indicates that the cortisol secretion is ACTH-independent, usually an adrenal tumor or hyperplasia. An ACTH concentration of greater than 15 pg/mL indicates ACTH-dependent hypercortisolism, usually of pituitary origin, or occasionally ectopic ACTH secretion. |
Plasma samples should be placed in plastic tubes and frozen
immediately. Avoid freeze/thaw cycles. |