|Adrenocorticotropic Hormone||ICMA||6 - 46||pg/mL|
|1||Plasma EDTA||1 (0.5) mL||Frozen - 31 Day(s)||Split into 2 plastic vials and freeze within 1 hour.|
|Aid in diagnosing disorders of the hypothalamic-pituitary system including ACTH-secreting tumors. In adrenal insufficiency, a concentration of ACTH greater than 100 pg/mL is diagnostic of primary adrenal insufficiency; whereas, patients with pituitary causes of adrenal insufficiency have ACTH concentrations in the normal range. In hypercortisolism (plasma cortisol greater than 15 ug/dL), an ACTH concentration of less than 5 pg/mL indicates that the cortisol secretion is ACTH-independent, usually an adrenal tumor or hyperplasia. An ACTH concentration of greater than 15 pg/mL indicates ACTH-dependent hypercortisolism, usually of pituitary origin, or occasionally ectopic ACTH secretion.|
Plasma samples should be placed in plastic tubes and frozen
immediately. Avoid freeze/thaw cycles.