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NAME | METHOD | REFERENCE RANGE | UNITS |
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Urine Free Cortisol | LC-MS-MS | view ref range | ug/24hr |
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Total Urine Volume | mL |
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TYPE | VOLUME | TEMPERATURE | INSTRUCTIONS |
PRIMARY | ||||
1 | Urine 24 hour | 10 (5) mL | Ambient - 48 Hour(s), Refrigerated - 7 Day(s), Frozen - 2 Month(s) | See COLLECTION INSTRUCTIONS. |
Assess adrenal function; particularly useful in the diagnosis of Cushing syndrome. Recent data suggest that urinary free cortisol concentrations can be significantly altered in patients taking inhaled corticosteroids (J Clin Endocrinol Metab 2002;87:4541-6). |
Acetic and boric acid are acceptable additives. Add 12.5 mL of
50% acetic acid or 5 g of boric acid at the start of a 24 hour collection. Measure the total volume, mix the specimen and transfer the aliquot to a clean, leakproof screw cap tube. Record the total volume on specimen container and requisition form. |