3251 Thyroglobulin Evaluation

Components
NAME METHOD REFERENCE RANGE UNITS
Thyroglobulin Autoantibodies ICMA  < 60  U/mL 
Thyroglobulin ICMA  view ref range  ng/mL 


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Serum 2 (0.4) mL   Ambient - 5 Day(s), Refrigerated - 7 Day(s), Frozen - 2 Month(s)  


Clinical utility
Autoantibodies to thyroglobulin are associated with chronic lymphocytic (Hashimoto) thyroiditis (76-100%), primary myxedema (72%), hyperthyroidism (33%), colloid goiter (8%), adenoma (28%), thyroid cancer (13-65%), and autoimmune disease. The prevalence in women is 18%, which increases with age (30%). The prevalence in men is lower (3-6%). High thyroglobulin values are reported with surgery or irradiation to the thyroid, with thyroiditis, T4-binding globulin deficiency, with administration of TRH, TSH, iodine, and with administration of anticancer drugs. High levels also occur in goiter and in many types of hyperthyroidism. Thyroglobulin Autoantibodies can interfere with the determination of Thyroglobulin. If specimen contains Thyroglobulin Autoantibodies, interpret Thyroglobulin result with caution.


Reported: Next day

CPT Code: 84432, 86800

Notes: Thyroglobulin Autoantibodies can intefere with the detemination of Thyroglobulin. If specimen contains Thyroglobulin Autoantibodies, interpret result with caution. Also available Thyroglobulin Serum, #3255.