8148 BK (Polyomavirus) DNA DetectR™

Components
NAME METHOD REFERENCE RANGE UNITS
Specimen Source      
BK Virus DNA RT-PCR  Not detected   


Specimen Requirements
TYPE VOLUME TEMPERATURE INSTRUCTIONS
PRIMARY
1 Plasma EDTA 2 (1) mL   Refrigerated - 7 Day(s), Frozen - 30 Day(s)  
ALTERNATE
  Plasma ACD 2 (1) mL   Refrigerated - 7 Day(s), Frozen - 30 Day(s)  
  Urine   Refrigerated - 7 Day(s), Frozen - 30 Day(s)  
  Whole Blood ACD 2 (1) mL   Ambient - 4 Day(s), Refrigerated - 4 Day(s)  
  Whole Blood EDTA 2 (1) mL   Ambient - 4 Day(s), Refrigerated - 4 Day(s)  


Clinical utility
BK virus-associated nephropathy has become increasingly recognized as the cause of renal dysfunction and kidney allograft loss in transplant patients. The BK virus can reactivate and cause disease in states of immunodeficiency, most frequently in renal and bone marrow transplant patients. BK virus disease is associated with hemorrhagic and non-hemorrhagic cystitis, ureteral stenosis, tubulointerstitial nephritis, compromised allograft function, and allograft failure. The diagnosis of the BK virus has relied heavily on biopsy-based evidence. This PCR-based assay can aid in the diagnosis of BKV reactivation and nephropathy.


Collection Instruction
Collect whole blood in EDTA K3 or ACD-A tube. Mix well. Centrifuge
and separate plasma. Place plasma in plastic tube for shipping.
Ship on cold pack or frozen on dry ice (preferred) by overnight
courier.


Reported: Same day

CPT Code: 87798

Notes: This assay will detect specific BK (Polyomavirus) DNA down to 200 copies/mL. This test is not approved for the testing of patient samples from New York State.